WarrZone 2003

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Wendy Warr has produced the following research papers in 2003.

W. A. Warr. High Throughput Chemistry. In Handbook of Chemoinformatics - From Data to Knowledge; Gasteiger, J. Ed.; Wiley-VCH: Weinheim 2003, Vol. 4, pp. 1604-1639.

Contents
10.4.2.1 Introduction
10.4.2.2 History
10.4.2.3 Split and Mix Synthesis
10.4.2.3.1 Deconvolution
10.4.2.3.2 Encoded Libraries
10.4.2.4 Solid-phase Synthesis
10.4.2.4.1 Reviews of Chemistry
10.4.2.4.2 Natural Product Chemistry
10.4.2.4.3 Resins
10.4.2.4.4 Linkers
10.4.2.4.5 Microarrays
10.4.2.5 Solution-phase Synthesis
10.4.2.5.1 Polymer-Assisted Solution-Phase Synthesis
10.4.2.5.2 Fluorous Mixture Synthesis
10.4.2.6 Combinatorial Biosynthesis
10.4.2.7 Dynamic Combinatorial Chemistry
10.4.2.8 Laboratory Instrumentation
10.4.2.8.1 Microwave Synthesis
10.4.2.8.2 Purification and Analysis
10.4.2.9 Information Sources
10.4.2.10 Data Management
10.4.2.10.1 Library Registration
10.4.2.10.2 Research Asset Management and Inventory Control
10.4.2.11 Library Design
10.4.2.12 Virtual High Throughput Screening
10.4.2.13 Conclusion
References

W. A. Warr. Evaluation of an Experimental Chemistry Preprint Server. J. Chem. Inf. Comput. Sci. 2003, 43, 362-373.

Abstract:

A preprint is a research article made publicly available prior to formal publication. A preprint server is a freely available archive and distribution medium for preprints, allowing rapid dissemination and use of multimedia and supporting files. Electronic eprints have been widely adopted in certain fields (notably high energy physics), but, until recently, the preprint concept has not been received with enthusiasm by most chemists. Despite the fact that preprints have the advantage of rapid publication, chemists have been reluctant to produce them because they could be viewed as "unallowable" for research assessment or tenure exercises or for publication in certain prestigious journals. In theory, preprints, together with version control and online discussion, could be a useful compromise: rapid prepublication followed by open peer review, before publication in a traditional journal. This paper constitutes a preliminary evaluation of a Chemistry Preprint Server in its second year of operation and summarizes the lessons that can be learned from the experiment to date.